https://www.selleckchem.com/pe....ptide/angiotensin-ii
Background A plethora of methods and models of disproportionality analyses for safety surveillance have been developed to date without consensus nor a gold standard, leading to methodological heterogeneity and substantial variability in results. We hypothesized that this variability is inversely correlated to the robustness of a signal of disproportionate reporting (SDR) and could be used to improve signal detection performances. Methods We used a validated reference set containing 399 true and false drug-event pairs