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Severe acute respiratory syndrome Coronavirus 2 (SARS CoV-2), the virus that causes COVID-19, and consequent social distancing directives have been observed to negatively impact social relationships but the impact of these changes on the quality of social relationships at a population level has not been explored. To evaluate changes in social relationships in a U.S. population sample during a time of social distancing. We deployed a matched, longitudinal survey design of the National Institutes of Health Adult Social Relationship Scales