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. Level III, retrospective cohort study. To establish a quantitative relationship between the Blackburne-Peel index and posterior tibial slope in both skeletally mature and skeletally immature individuals and to evaluate the rate at which variation in tibial slope influences changes in patellar height categorization as normal, patella alta, and patella baja. A consecutive series of lateral knee radiographs were retrospectively reviewed. Radiographs were excluded for rotation, inadequate visible proximal tibia length, a

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05). The µTBS decreased significantly with aging (5000 thermocycles) (p less then 0.05). BQ cement resulted in the highest μTBS to GR treated with TiF4 2% wt/v + CB compared to the other groups (p less then 0.05). Aged GR/BQ treated with TiF4 2% wt/v + CB had the highest predicted µTBS (19 MPa). CONCLUSION TiF4 2% wt/v followed by silane application enhanced the adhesion of GR/BQ and LU/BQ systems. On the other hand, HF surface treatment followed by silane application improved the adhesion of the VE/BQ system.PURPOSE To determine the

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In E. coli dihydrofolate reductase, unusual conformational motions of a functional M20 loop that interacts with substrate and coenzyme have been construed as evidence for dynamical effects in enzyme catalysis. By computing this loop's conformational free energies in the apoenzyme, we show that it is sensitive to the treatment of long-range electrostatic interactions and the solvation box size in modeling/simulations. These results provide important guidelines for computing reaction/binding free energy profiles of proteins

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