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According to the NWM and SUCRA evaluations, ICG+NIR diode laser therapy demonstrates superior acne treatment efficacy compared to other RCT-based PDT methods. Care must be taken in drawing conclusions from this study, owing to its inherent limitations. In acne treatment, the NWM and SUCRA ranking indicates that the ICG + NIR diode laser is more effective than other PDTs, derived from the RCTs. Nevertheless, the findings presented here necessitate a cau