https://www.selleckchem.com/pr....oducts/SB-216763.htm
Policymakers will require substantial debate and the involvement of various stakeholders to implement this recommendation.Conophylline (CNP) is a vinca alkaloid extracted from the Tabernaemontana divaricata plant. It has been reported that CNP induces autophagy in a mammalian target of rapamycin (mTOR)-independent manner, thereby inhibits protein aggregation. However, the mode of action of CNP in inducing autophagy remains unknown. In this study, we identified glutathione peroxidase 4 (GPX4) as a CNP-binding protein by using thermal p