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Based on laboratory reference intervals, low taurine concentrations were common in English ****er spaniels with dilated cardiomyopathy, showing a possible association between dilated cardiomyopathy in English ****er spaniels and taurine deficiency; supplementation with taurine was not curative. Based on laboratory reference intervals, low taurine concentrations were common in English ****er spaniels with dilated cardiomyopathy, showing a possible association between dilated cardiomyopathy in English ****er spaniels and taurine deficienc