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3-fold. In the cold-water tail flick and formalin tests, significant increases of the antinociceptive effects of morphine were also observed when combined with CRAs. CONCLUSIONS These results support the potential of a new "opioid-sparing" approach for pain treatment, which combines CRAs with reduced doses of morphine. © Association of Military Surgeons of the United States 2020. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.INTRODUCTION The objective was to determine if the Mobile Device Outcomes-bas