Tofacitinib 5 mg (Tofacent) is an oral medication used primarily to treat autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. As a Janus kinase (JAK) inhibitor, it works by blocking specific enzymes that contribute to the inflammatory process in these diseases. Tofacitinib helps reduce symptoms like pain, swelling, and joint damage in arthritis and manages symptoms of ulcerative colitis, promoting mucosal healing. It requires regular monitoring by healthcare professionals due to potential side effects, including infections, elevated liver enzymes, and blood lipid changes. Tofacitinib provides an effective treatment option for patients unresponsive to traditional therapies.