https://www.selleckchem.com/pr....oducts/tiplaxtinin-p
SUMMARY Bulk RNA sequencing studies have demonstrated that human leukocyte antigen (HLA) genes may be expressed in a cell type-specific and allele-specific fashion. Single-cell gene expression assays have the potential to further resolve these expression patterns, but currently available methods do not perform allele-specific quantification at the molecule level. Here we present scHLAcount, a postprocessing workflow for single-cell RNA-seq data that computes allele-specific molecule counts of the HLA genes based on a persona
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