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nts and so on. We plan to publish the results in a peer-reviewed high-quality journal for professionals. In addition, we also plan to publish it for lay readers in order to maximalise the dissemination and benefits of this trial. ClinicalTrials.gov NCT04164602. ClinicalTrials.gov NCT04164602. To analyse characteristics and developmental trends of clinical study registration primarily sponsored by China's institutions during 2009-2018. Registration information registered prior to 31 December 2018 was obtained from the International Clinical