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959). In contrast, among frail patients, DM was significantly associated with a higher incidence of events (HR 1.51, p=0.034). Unlike frailty status, DM was not associated to poorer long-term outcome in elderly patients with ACS. Among frail patients the presence of DM seems to provide additional prognostic information. Unlike frailty status, DM was not associated to poorer long-term outcome in elderly patients with ACS. Among frail patients the presence of DM seems to provide additional prognostic information.Nutritional alterations are highly prevalent in