https://www.selleckchem.com/pr....oducts/gsk591-epz015
We find public TCR-β sequences at higher abundances compared with unshared sequences in the productive, but not in the non-productive, repertoire. We show that neutral processes such as recombination biases, codon degeneracy and generation probability do not fully account for these differences, and conclude that thymic or peripheral selection plays an important role in increasing the abundances of public TCR-β sequences. Cranial vault modification (CVM), the intentional reshaping of the head, indicated group affiliat