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Luciferase activities of wild‑type and mutant PWAR6 and BMP2 were assessed by conducting a dual‑luciferase reporter assay. The results indicated that PWAR6 expression was upregulated in OM‑incubated hPDLSCs compared with GM‑incubated hPDLSCs, and PWAR6 overexpression increased the osteogenic differentiation and mineralization of hPDLSCs compared with the corresponding control group. By contrast, miR‑106a‑5p expression was downregulated in OM‑incubated hPDLSCs compared with GM‑incubated hPDLSCs. PWAR6 acted as a sponge of miR‑106a‑5p and
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