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4 Bq·L-1. On the other hand, considering the cost and potential environmental impact of present available ****tails, the system with 20-ml vials is recommended for determining the sample with the specific activity higher than 2 Bq·L-1.Three new ruthenium(II) complexes were synthesized from different substituted isothiazole ligands 5-(methylamino)-3-pyrrolidine-1-ylisothiazole-4-carbonitrile (1), 5-(methylamino)-3-(4-methylpiperazine-1-yl)isothiazole-4-carbonitrile (2) and 5-(methylamino)-3-morpholine-4-ylisothiazole-4-carbonitrile (3) [