https://www.selleckchem.com/pr....oducts/oligomycin.ht
Therefore, compound DC-K2in212 could serve as a potential CDK2 inhibitor for further development.Colchicine shows very high antimitotic activity, therefore, it is used as a lead compound for generation of new anticancer agents. In the hope of developing novel, useful drugs with more favourable pharmacological profiles, a series of doubly modified colchicine derivatives has been designed, synthesized and characterized. These novel carbamate or thiocarbamate derivatives of 10-demethoxy-10-methylaminocolchicine have been tested for thei