https://www.selleckchem.com/pr....oducts/ag-221-enasid
Unipotent male germline stem (GS) cells can undergo spontaneous reprogramming to germline pluripotent stem (GPS) cells during in vitro culture. In our previous study, we proposed a Boolean logical model of gene regulatory network (GRN) during reprogramming of GS cells to GPS cells. This study was designed to predict and model synergistic microRNA (miRNA) regulatory network during reprogramming of GS cells into GPS cells. The miRNAs targeting differentially expressed genes (DEGs) among GS and GPS cells were predicted by a novel