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Analysis of the organic constituents extracted from the red algae Laurencia majuscula, gathered from the Hurghada reef in the Red Sea, yielded five C15 acetogenins, encompassing four tricyclic maneonenes (1-4) and a five-membered acetogenin (5). The extract additionally contained fifteen sesquiterpenes, consisting of seven lauranes (6-12), one cuparane (13), one seco-laurane (14), one snyderane (15), two chamigranes (16, 17), two rearranged chamigranes (18, 19), one aristolane (2, a tricyclic diterpene (21), and a chlorinated fatty acid derivative (22). Co
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