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The glycan guests bound within their SCR hosts in one of three supramolecular geometries center-parallel, center perpendicular, and off-center. Many host•guest combinations formed higher stoichiometry complexes, 21 glycan•SCR or 12 glycan•SCR , where the former are driven by positive allosteric cooperativity induced by glycan-glycan contacts. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.INTRODUCTION Communication in the biomedical sciences and clinical practice would be clearer if everyone used the same set of technical terms.