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This chapter will focus on the imperative of studying spermatogenesis, including a detailed introduction to spermatogonia and stem cell spermatogonia (SSCs), and presenting the need for precise definitions of SSCs and experimental protocols that enable the distinction of the diverse spermatogonial cell types within the mammalian testis. The leading brain tumor, Glioblastoma Multiforme (GBM), is r
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