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Wild-type (WT) and other strains of mice were evaluated to determine their relative susceptibility to infection. Hematoxylin and eosin (HE) staining and immunohistochemical staining protocols were used to analyze the pathological modifications within each organ caused by fibulin-2. The wild-type mice group and the mice group. A comprehensive analysis included 132 patients within the scope of this study. The fibulin-2 level wa