https://pinometostatinhibitor.....com/driving-the-glob
Following molecular docking of approximately 200 potent ACEi peptides, 20 were selected for cellular and in vitro enzymatic activity assessments. Subsequently, five of these peptides were orally administered at a dose of 15 mg/kg body weight daily for seven days to spontaneously hypertensive rats. Significant antihypertensive activity was observed in IKW and RIY peptides, correlating with the activation of circulating/aortic ACE2, elevated circulating Ang (1-7), and decreased lev