https://www.selleckchem.com/pr....oducts/corticosteron
Break-induced ****tion (BIR) repairs one-ended double-strand breaks in DNA similar to those formed by ****tion collapse or telomere erosion, and it has been implicated in the initiation of genome instability in cancer and other human diseases1,2. Previous studies have defined the enzymes that are required for BIR1-5; however, understanding of initial and extended BIR synthesis, and of how the migrating D-loop proceeds through known ****tion roadblocks, has been precluded by technical limitations. Here we use a newly deve
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