https://bi1744agonist.com/noso....comial-sars-cov-2-tr
Because they are situated far away from both the active and substrate binding sites, the means by which they exert their effect is not immediately apparent. To elucidate the autoinhibition of PP2A, we meticulously combined allosteric pathway analysis from molecular dynamics simulations with corroborative biochemical experiments. Wild-type (WT) regulatory subunit B56's C-arm blocks the active and substrate-binding sites, enforcing
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