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eCRS was characterized by the presence of greater than ten eosinophils per high-power field (HPF). Subjects who did not present with CRS or asthma were selected as controls. Compared to the control group, CRS with NP (CRSwNP) showed increased EPX levels (p=0.0007). EPX levels were also higher in eCRS than in neCRS (p=0.0002). eCRSwNP and eCRSsNP both displayed significantly higher EPX levels than neCRSsNP (p=0.