https://www.selleckchem.com/pr....oducts/wnt-c59-c59.h
RNA-sequencing analysis revealed significant down-regulation of only five genes in adult thrb -/- retina, of which three (lws1, lws2, and miR-726) occur in a single syntenic cluster. In the thrb -/- retina, retinal progenitors destined to become red cones were transfated into ultraviolet (UV) cones and horizontal cells. Taken together, our findings demonstrate cooperative regulation of cyp27c1 by TH receptors and a requirement for thrb in red cone fate determination. Thus, TH signaling coordinately regulates both spectral sensitivit
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