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The current study highlights ETS1's role in promoting ccRCC proliferation by increasing MMP2 levels; simultaneous silencing of ETS1 and ERK inhibition can powerfully suppress ccRCC proliferation, migration, and invasion. The therapeutic and prognostic potential of ETS1 may be significant in renal cell carcinoma. Due to its prevalence as the second-most common neurodegenerative disease, Parkinson's disease has a considerable impact on a patient's mobility and quality of life. The symptoms of Parki