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26, 95%CI (-0.45, -0.08), P = 0.005]; (3) the cumulative prednisone dosage-the MMF group was lower than that in the control group [standardized mean difference (SMD) = -0.32, 95%CI (-0.53, -0.11), P = 0.003]; (4) incidence of adverse reactions-there was no significant difference between the MMF group and the control group [RD = 0.02, 95%CI (-0.04, 0.09), P = 0.46]. Conclusion The therapy of mycophenolate mofetil in the treatment of SDNS or FRNS in children has a certain advantage in reducing the number of relapses and cumulative predni