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Synaptic changes during postnatal development are fundamental for the maturation of neural networks. The maturation of excitatory synapses is spatially coordinated within the dendritic spines, whose growth and pruning are dynamically regulated. Striatal spiny projection neurons (SPNs) are targeted by excitatory signals originating in the cerebral cortex and thalamus. The developmental backgrounds and operational roles of striatonigral d
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