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Inflammatory polyps (IPs) in inflammatory bowel disease may have been associated in the past with increased neoplasia risk. Additionally, colonic mucosa in filiform polyposis and giant inflammatory polyposis may be difficult to visualize during endoscopic surveillance, perhaps contributing to early colectomy in these patients. To examine the clinicopathologic characteristics and significance of IPs and inflammatory polyposis in inflammatory bowel disease. We identified 336 resections from inflammatory bowel disease patients (212 [63.1%]