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The proposed approach was also compared to another method based on a CNN architecture called Inception-v3 and manual search to quantify hyperparameter values. The comparison results showed that the GSA-DenseNet121-COVID-19 was able to beat the comparison method, as the second was able to classify only 95% of the test set samples. The proposed GSA-DenseNet121-COVID-19 was also compared with some related work. The comparison results showed that GSA-DenseNet121-COVID-19 is very competitive. Systemic rheumatic diseases are characterized by