https://unc0646inhibitor.com/l....c-qtofms-presumptive
Gene transcription is suppressed by Polycomb repressive complex 2 (PRC2), a complex deeply involved in embryonic development, through the methylation of lysine 27 on histone H3 (H3K27). In the PRC2 core complex, EZH2 is the catalytic component, and EED's allosteric activation of EZH2 is specifically triggered by its binding to trimethylated H3K27 (H3K27me3). The