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Of the patients in the pre-transition group, there were 126 in total, divided into 123 treated with heparin and 3 treated with bivalirudin. In contrast, the post-transition group contained 275 patients, with 82 treated with heparin and 193 treated with bivalirudin. Drug costs were evaluated using the wholesale acquisition cost, and reimbursement fee schedules were used to assess laboratory assay costs. Using the duration of each ECMO run as a normalization factor, cost da