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These research outcomes hold the potential to refine risk assessment in ESRD patients getting TAVR. Our findings indicate that ESRD patients receiving midodrine are characterized by a higher degree of severity and face a reduced likelihood of survival after TAVR compared to ESRD patients not taking midodrine. The risk stratification of ESRD patients undergoing TAVR procedures might be enhanced by leveraging these findings. In heart failure patients, cardiac sympathetic nerve act