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In South Africa, age-disparate to ****ual relationships where the age difference between partners is 5years or greater is an important contributor to the spread of HIV. However, little is known about the predictors of age-disparate ****ual relationships. This study investigates factors associated with age-disparate ****ual relationships among males and females in South Africa. This analysis used the 2012 nationally representative population-based household survey conducted using multi-stage stratified cluster sampling design. Multivariate