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02) and 8.8 months (95% CI -1.26, -0.2, respectively. Other adversities indicators, cumulative adversities, and mono were not statistically associated with menarcheal timing. These findings provided some support for the growing evidence that early life experiences may influence the reproductive development in girls.To our knowledge, this is the first report on a machine-learning-assisted Brillouin optical frequency domain analysis (BOFDA) for time-efficient temperature measurements. We propose a convolutional neural network (CNN)-base