https://www.selleckchem.com/pr....oducts/pf-06873600.h
as a self-limiting mechanism to control and resolve excessive inflammation and oxidative stress in the lung during sepsis.Mechanical stimulation plays a crucial part in the development of intervertebral disc degeneration (IDD). Extracellular matrix (ECM) stiffness, which is a crucial mechanical microenvironment of the nucleus pulposus (NP) tissue, contributes to the pathogenesis of IDD. The mechanosensitive ion channel Piezo1 mediates mechanical transduction. This study purposed to investigate the function of Piezo1 in human NP cell