https://cort125134antagonist.c....om/endemic-as-well-a
Biliary excretion and metabolic pathways are responsible for the elimination of S-3100-CA, which is first transported to the liver. In prior investigations involving human PBPK modeling, we achieved accurate prediction of S-3100-CA pharmacokinetics. This was accomplished by obtaining human liver parameters from chimeric mice with humanized livers, following validation against quantitative metrics based on mo