https://www.selleckchem.com/pr....oducts/Gefitinib.htm
While RV infection induced minimal changes to TJs, the IL-13-matured hNECs has reduced capacity for upregulation of IFN-λ1 and CXCL10 but further increased the expression of TSLP upon RV infection. These findings suggested that IL-13-mediated dysfunction of TJs and compromised epithelial barrier. IL-13-induced cilia loss conferred lowered viral ****tion and impaired antiviral responses of nasal epithelium against RV infection.Protein ubiquitylation is an important posttranslational modification (PTM), which is involved in diverse b