https://www.selleckchem.com/pr....oducts/kd025-(slx-21
To date, smoking and silica exposure have been reproducibly demonstrated to trigger the emergence of RA. However, many other environmental factors have been studied, mostly with a case-control design. Results were conflicting and studies rarely considered potential gene-environment interactions. There is a need for large scale prospective studies and studies in predisposed individuals to better understand and prevent the disease and its course. To date, smoking and silica exposure have been reproducibly demonstrated to trigger