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We aimed to investigate fertilisation rates, quality of embryo, pregnancy and live birth rates, endocrine, ****ual function, psychological status and quality of life of cases diagnosed with Klinefelter syndrome (KS). Clinical findings, hormone values and semen analyses in patients with nonmosaic KS (Group 1, n=121) and those with non-genetic nonobstructive azoospermia (NOA) (Group 2, n=178) were retrospectively analysed. Sperm retrieval outcomes with microdissection testicular sperm extraction (micro-TESE), fertilisation rates and embryo