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Our Cox regression model showed that PP had a higher risks (RR=1.7; CI 95% 1.1-2.6) of revision, when compared with LP (p=0.026). The risk of revision for any reason and that of early conversion to total knee arthroplasty (TKA) after high tibia osteotomy were significantly increased for PP, when compared with LP. The risk of revision for any reason and that of early conversion to total knee arthroplasty (TKA) after high tibia osteotomy were significantly increased for PP, when compared with LP.Amphibians such as Xenopus tropicalis exhibi