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The findings provided deep insight into the prescription-formulating principle in DZXX for treating the cerebrovascular diseases. © 2020 Wiley Periodicals, Inc.Broad application of reduced graphene oxide (rGO) and ubiquitous lead (Pb) pollution may increase the possibility of combined exposure of humans. Information on the combined effects of rGO and Pb in human cells is scarce. This work was designed to explore the potential effects of rGO on Pb-induced toxicity in human alveolar epithelial (A549) cells. Prepared rGO was polycrystalli