https://www.selleckchem.com/pr....oducts/sar439859.htm
The aims of the present study were to evaluate the immunogenicity of an inactivated rabies vaccine based on the ERAGS strain. The ERAGS virus propagated in Vero cells was inactivated with 3 mM binary ethylenimine for 8 hours. Three types of inactivated rabies vaccines were prepared to determine the minimum vaccine virus titers. Four further types of inactivated rabies vaccines were prepared by blending inactivated ERAGS with four different adjuvants; each vaccine was injected into mice, guinea pigs, and dogs to identify the optimal ad