https://www.selleckchem.com/pr....oducts/kd025-(slx-21
Pegylated liposomal doxorubicin (PLD) is widely utilised in cancer chemotherapy, but exhibits large inter-individual pharmacokinetic variability and **** differences in plasma clearance. Population pharmacokinetic modelling has suggested PLD plasma clearance correlates with peripheral monocyte counts, while **** hormones are known to affect endocytosis and phagocytosis in mononuclear cells. This study investigated whether **** hormones affect the uptake of PLD by human monocytes and macrophages in vitro. 17β-estradiol, but not tes
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