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DG's mechanism of action involved upregulating FXR and SHP expression and downregulating hepatic de novo lipogenesis genes like SREBP1C, ACC1, and FASN. DG, correspondingly, supported the expression of peroxisome proliferator-activated receptor alpha (PPAR), which is instrumental in the breakdown of fatty acids. Moreover, DG diminished the expression of the CD36 protein, which governs the transport of fatty