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Sexually transmitted infections (STIs) are prevalent in Ethiopia and elsewhere among different population groups particularly among female **** workers (FSWs). Because of their work and their behavior, FSWs are at high risk to acquire STIs. The aim of the study was to assess the seroprevalence and associated factors of HIV, HBV, HCV, and among FSWs in Dessie City, Northeast Ethiopia. This cross-sectional study was conducted in Dessie City, Amhara Region, Northeastern Ethiopia, from November 2017 to April 2018. A total of 360 FSWs whose ag