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e., deficits across all domains). A dose-response relationship between baseline level of impairment and subsequent risk of progression to dementia was evident for aMCI profiles after controlling for age, ****, and education. Machine learning more easily classified participants with aMCI in comparison to SCD (8% vs. 21% misclassified). Cognitive performance follows distinct patterns, especially within aMCI. The patterns map onto risk of progression to dementia. Cognitive performance follows distinct patterns, especially within aMCI. The