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6%) and 50 (63%) combined episodes, respectively (p 0.001). Compared to the 4ICS group, the 2ICS group presented a relative risk of 0.06 (IC 0.02-0.21, p 0.001) and number needed to treat (NNT) of 2.1. No adverse events occur derived from the NTC placement. NTC tip placement in the 2ICS compared to 4ICS decreases the incidence of the combined number of dysfunction, repositioning and relocation episodes, with a NNT of 2 for its prevention. NTC tip placement in the 2ICS compared to 4ICS decreases the incidence of the combined number