https://www.selleckchem.com/pr....oducts/ly3039478.htm
Photothermal therapy (PTT) based on aggregation-induced emission luminogen (AIEgen) is very promising for superficial tumor therapy due to the superior photostability and photothermal conversion efficiency of AIEgens. However, the systemic administration of AIEgen remains challenging, mainly because of solubility dissatisfaction and biodistribution. Here, a dissolving microneedle (MN) system loaded with AIEgen (NIR95 was developed for topical administration to treat malignant skin tumor melanoma. Firstly, NIR950-loaded polymeric mic