https://mek-signaling.com/inde....x.php/phytopythiumli 
  Our in vitro study of CD8+ T cell cytotoxicity revealed that in vitro-activated CD8+ T cells from aged mice demonstrated enhanced cytotoxic ability compared to those from young mice. Menin-deficient effector T cells, analogous to senescent CD8+ T cells, had elevated cytotoxic activity and NK receptor expression. Moreover, CD8+ T cells lacking Menin can destroy tumor cells without requiring antigen recognitio
 
					 
						 
                                     
				    				